scPDB - Distribution of Binding site Similarity values of 2hx4 entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2hx4	H4B	Nitric oxide synthase, brain	1.14.13.39

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2hx4	H4B	Nitric oxide synthase, brain	1.14.13.39	1.000
4fvx	H4B	Nitric oxide synthase, brain	1.14.13.39	0.878
4lux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.870
4jsi	H4B	Nitric oxide synthase, brain	1.14.13.39	0.855
3b3n	H4B	Nitric oxide synthase, brain	1.14.13.39	0.852
3b3o	H4B	Nitric oxide synthase, brain	1.14.13.39	0.827
3nnz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.817
4cx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.805
1zzr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.804
3fc5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.800
4fvz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.800
2g6i	HBI	Nitric oxide synthase, brain	1.14.13.39	0.793
3b3p	H4B	Nitric oxide synthase, brain	1.14.13.39	0.792
3ufu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.789
1k2t	H4B	Nitric oxide synthase, brain	1.14.13.39	0.779
1k2u	H4B	Nitric oxide synthase, brain	1.14.13.39	0.773
1p6k	H4B	Nitric oxide synthase, brain	1.14.13.39	0.773
1rs7	H4B	Nitric oxide synthase, brain	1.14.13.39	0.772
3ufq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.772
3pnf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.767
3png	H4B	Nitric oxide synthase, brain	1.14.13.39	0.762
3jt7	H4B	Nitric oxide synthase, brain	1.14.13.39	0.761
3jx2	H4B	Nitric oxide synthase, brain	1.14.13.39	0.760
3rqj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.760
1rs6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.759
3rqm	H4B	Nitric oxide synthase, brain	1.14.13.39	0.757
3jx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.752
3nln	H4B	Nitric oxide synthase, brain	1.14.13.39	0.752
3nlp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.751
1mmv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.746
3jwv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.746
1m00	H4B	Nitric oxide synthase, brain	1.14.13.39	0.745
4jsh	H4B	Nitric oxide synthase, brain	1.14.13.39	0.735
3nlz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.733
3jt5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.731
1p6j	H4B	Nitric oxide synthase, brain	1.14.13.39	0.723
4fw0	H4B	Nitric oxide synthase, brain	1.14.13.39	0.721
3nlj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.715
3jt9	H4B	Nitric oxide synthase, brain	1.14.13.39	0.707
3b3m	H4B	Nitric oxide synthase, brain	1.14.13.39	0.701
3jwt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.695
4jsf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.690
1zzq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.687
3jt8	H4B	Nitric oxide synthase, brain	1.14.13.39	0.686
3ufv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.680
3ufr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.678
1om5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.676
4k5g	H4B	Nitric oxide synthase, brain	1.14.13.39	0.675
3n5z	H4B	Nitric oxide synthase, brain	1.14.13.39	0.673
3n5y	H4B	Nitric oxide synthase, brain	1.14.13.39	0.672
4k5d	H4B	Nitric oxide synthase, brain	1.14.13.39	0.672
3q9a	H4B	Nitric oxide synthase, brain	1.14.13.39	0.670
3jwu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.669
4jsg	H4B	Nitric oxide synthase, brain	1.14.13.39	0.669
3tym	H4B	Nitric oxide synthase, brain	1.14.13.39	0.666
4fvy	H4B	Nitric oxide synthase, brain	1.14.13.39	0.666
3pne	H4B	Nitric oxide synthase, brain	1.14.13.39	0.665
3nny	H4B	Nitric oxide synthase, brain	1.14.13.39	0.664
3dqr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.662
4cx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.661
2hx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.659
2g6j	7AP	Nitric oxide synthase, brain	1.14.13.39	0.657
3hsn	H4B	Nitric oxide synthase, brain	1.14.13.39	0.657
4eux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.654
3svq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.651
3jt6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.650
5agl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.648
3nlo	H4B	Nitric oxide synthase, brain	1.14.13.39	0.646
3jx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.644
3svp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.644
4k5e	H4B	Nitric oxide synthase, brain	1.14.13.39	0.644
1zzu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.643
3nlw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.643
4imt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.643
5agp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.642
3nlr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.641
3q99	H4B	Nitric oxide synthase, brain	1.14.13.39	0.639
4cx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.639
3ufw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.636
3jt3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.635
3rqk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.635
3jta	H4B	Nitric oxide synthase, brain	1.14.13.39	0.634
4gqe	H4B	Nitric oxide synthase, brain	1.14.13.39	0.633
5agk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.633
3nlk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.632
3nlq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.630
3ufo	H4B	Nitric oxide synthase, brain	1.14.13.39	0.626
3ufp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.626
3e7g	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.625
3ufs	H4B	Nitric oxide synthase, brain	1.14.13.39	0.625
3tyl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.615
3n5v	H4B	Nitric oxide synthase, brain	1.14.13.39	0.612
3nly	H4B	Nitric oxide synthase, brain	1.14.13.39	0.612
3jt4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.610
3rql	H4B	Nitric oxide synthase, brain	1.14.13.39	0.610
4k5f	H4B	Nitric oxide synthase, brain	1.14.13.39	0.605
1k2s	H4B	Nitric oxide synthase, brain	1.14.13.39	0.602
3nos	H4B	Nitric oxide synthase, endothelial	1.14.13.39	0.601
3ej8	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.597
3jx6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.596
4imw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.593
1zvl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.592
3uft	H4B	Nitric oxide synthase, brain	1.14.13.39	0.588
4d1o	H4B	Nitric oxide synthase, endothelial	1.14.13.39	0.585
1r35	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.574
3e6o	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.573
3e6t	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.573
3jx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.569
2nod	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.568
3nlv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.563
3dwj	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.557
4imu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.549
3nod	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.544
3nw2	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.544
1m8e	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.535
4jse	H4B	Nitric oxide synthase, brain	1.14.13.39	0.530
3n61	H4B	Nitric oxide synthase, brain	1.14.13.39	0.529
1dwx	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.525
3e67	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.508
1vaf	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.500
1qom	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.490
1m9t	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.488
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.485
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.453
1m8i	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.451