Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2givACOHistone acetyltransferase KAT8

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2givACOHistone acetyltransferase KAT8/1.000
2ou2ACOHistone acetyltransferase KAT5/0.613
2y0mACOHistone acetyltransferase KAT8/0.596
1mj9COAHistone acetyltransferase ESA1/0.593
1mjbACOHistone acetyltransferase ESA1/0.584
3to6LYS_CMCHistone acetyltransferase ESA1/0.584
1fy7COAHistone acetyltransferase ESA1/0.583
1mjaCOAHistone acetyltransferase ESA1/0.559
3d91REMRenin3.4.23.150.450
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.446
1p0hCOAMycothiol acetyltransferase2.3.1.1890.445
1ozpACOMycothiol acetyltransferase2.3.1.1890.444
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.444
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.441
4lx9ACON-alpha-acetyltransferase2.3.10.441
3r96ACOMccE protein/0.440