sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 1.000 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.546 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.515 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.488 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.483 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.477 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.474 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.469 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.466 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.462 | |
| 5dp2 | NAP | CurF | / | 0.457 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.455 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.452 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.449 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.448 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.447 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.447 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.446 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.443 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.441 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.440 |