Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2flhZEACytokinin-specific binding protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2flhZEACytokinin-specific binding protein/1.000
4psbGA3Cytokinin-specific binding protein/0.584
4q0kGA3Phytohormone-binding protein/0.561
4a83DXCMajor pollen allergen Bet v 1-A/0.482
1nhqFADNADH peroxidase1.11.1.10.461
3f63GTXGlutathione transferase GST1-4/0.460
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.460
3qj0QI3Botulinum neurotoxin type A3.4.24.690.449
2cekN8TAcetylcholinesterase3.1.1.70.448
1qtiGNTAcetylcholinesterase3.1.1.70.447
3af1GDPPantothenate kinase2.7.1.330.447
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.444
3qizQI2Botulinum neurotoxin type A3.4.24.690.444
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.443
3g7jGTXGlutathione transferase GST1-4/0.442
2iko7IGRenin3.4.23.150.441
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.441
2whqHI6Acetylcholinesterase3.1.1.70.441
1hfqMOTDihydrofolate reductase1.5.1.30.440
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.440
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.440