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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2djlFMNDihydroorotate dehydrogenase (fumarate)1.3.98.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2djlFMNDihydroorotate dehydrogenase (fumarate)1.3.98.11.000
2djxFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.686
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.639
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.621
3c3nFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.619
3gyeFMNDihydroorotate dehydrogenase (fumarate)/0.619
4wzhFMNDihydroorotate dehydrogenase (fumarate)/0.606
2bslFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.583
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.575
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.566
3oixFMNDihydroorotate dehydrogenase/0.538
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.456
3ahn3A1Oligopeptidase/0.452
1jubFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.450
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
4eb5PLPCysteine desulfurase IscS 2/0.444
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.442
1tehNADAlcohol dehydrogenase class-31.1.1.10.441
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.441
5d3qGDPDynamin-13.6.5.50.440