sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 1.000 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.677 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.450 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.444 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.441 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 |