Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 1.000 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.494 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.466 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.463 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.456 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.446 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.445 |