sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2c3o | TPP | Pyruvate synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2c3o | TPP | Pyruvate synthase | / | 1.000 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.638 | |
| 2pda | TPP | Pyruvate synthase | / | 0.623 | |
| 2uza | HTL | Pyruvate synthase | / | 0.620 | |
| 2c3u | 2TP | Pyruvate synthase | / | 0.602 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.574 | |
| 1kek | HTL | Pyruvate synthase | / | 0.547 | |
| 2c3y | HTL | Pyruvate synthase | / | 0.531 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.474 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.466 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.465 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.461 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 5doz | NDP | JamJ | / | 0.458 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.455 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit alpha | / | 0.455 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit beta | / | 0.455 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.448 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.447 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.444 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.444 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.443 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.440 |