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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.619
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.601
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.596
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.550
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.538
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.529
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.529
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.518
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.507
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.471
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1xe55FEPlasmepsin-23.4.23.390.443
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442