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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2bhpNAD1-pyrroline-5-carboxylate dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2bhpNAD1-pyrroline-5-carboxylate dehydrogenase/1.000
2ehuNAD1-pyrroline-5-carboxylate dehydrogenase/0.640
2j40NAD1-pyrroline-5-carboxylate dehydrogenase/0.578
2j5nNAD1-pyrroline-5-carboxylate dehydrogenase/0.575
2ehqNAP1-pyrroline-5-carboxylate dehydrogenase/0.572
2eiiNAD1-pyrroline-5-carboxylate dehydrogenase/0.571
4pz2NADAldehyde dehydrogenase 2-6/0.522
2onpNADAldehyde dehydrogenase, mitochondrial1.2.1.30.490
3hazNADBifunctional protein PutA/0.490
4v37NADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.490
4fqfNADAldehyde dehydrogenase, mitochondrial1.2.1.30.488
1bxsNADRetinal dehydrogenase 11.2.1.360.486
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.481
1o04NADAldehyde dehydrogenase, mitochondrial1.2.1.30.481
2bjaNAD1-pyrroline-5-carboxylate dehydrogenase/0.473
2onmNADAldehyde dehydrogenase, mitochondrial1.2.1.30.467
1o00NADAldehyde dehydrogenase, mitochondrial1.2.1.30.460
4pt0NADAldehyde dehydrogenase/0.458
4wb9NAIRetinal dehydrogenase 11.2.1.360.452
4oe2NAD2-aminomuconate 6-semialdehyde dehydrogenase/0.449