sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 1.000 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.531 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.522 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.521 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.504 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.501 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.493 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.488 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.479 | |
| 4jxr | ACO | Acetyltransferase | / | 0.479 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.474 | |
| 3f8k | COA | Uncharacterized protein | / | 0.473 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.472 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.470 | |
| 4kub | COA | Uncharacterized protein | / | 0.469 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.466 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.465 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.463 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.462 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.461 | |
| 4oae | CLM | Uncharacterized protein | / | 0.461 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.460 | |
| 2prb | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.460 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.460 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.460 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.457 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.453 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.453 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.451 | |
| 2vbq | BSJ | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.450 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.448 | |
| 4r57 | ACO | Spermidine N(1)-acetyltransferase | / | 0.445 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.444 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.442 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.442 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.442 | |
| 2vqy | ACO | AAC(6')-Ib | / | 0.442 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.440 | |
| 1s7l | COA | Acetyl transferase | / | 0.440 |