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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1zm4TADExotoxin A2.4.2.36

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1zm4TADExotoxin A2.4.2.361.000
3b82NADExotoxin A2.4.2.360.579
3b8hNADExotoxin A2.4.2.360.577
2zitNADExotoxin A2.4.2.360.559
4bj9UHBTankyrase-22.4.2.300.497
3b78NADExotoxin A2.4.2.360.488
1dtpAPUDiphtheria toxin/0.483
3u9y09LTankyrase-22.4.2.300.483
5ds309LPoly [ADP-ribose] polymerase 12.4.2.300.463
1ddtAPUDiphtheria toxin/0.458
4li81XQTankyrase-12.4.2.300.441
4tkg09LTankyrase-22.4.2.300.440