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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1zbdGTPRas-related protein Rab-3A

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1zbdGTPRas-related protein Rab-3A/1.000
3oesGNPGTPase RhebL1/0.616
2gilGTPRas-related protein Rab-6A/0.593
5dhaGNPGTP-binding nuclear protein Ran/0.592
1xtsGTPGTP-binding protein Rheb/0.580
3lawGNPRas-related protein Rab-7a/0.578
1t91GTPRas-related protein Rab-7a/0.573
1yzqGNPRas-related protein Rab-6A/0.562
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.562
3w3zGTPGTP-binding nuclear protein Ran/0.561
2fe4GDPRas-related protein Rab-6B/0.560
3bbpGTPRas-related protein Rab-6A/0.556
3e5hGNPRas-related protein Rab-28/0.555
3a6pGTPGTP-binding nuclear protein Ran/0.549
4o25GTPGTP-binding protein Rheb/0.548
3nbzGTPGTP-binding nuclear protein Ran/0.547
2ffqGSPRas-related protein Rab-6B/0.545
1xtrGNPGTP-binding protein Rheb/0.543
2zetGTPRas-related protein Rab-27B/0.543
3oiuGNPGTPase HRas/0.543
1vg8GNPRas-related protein Rab-7a/0.541
1yhnGTPRas-related protein Rab-7a/0.527
4lhwGNPRas-related protein Rab-8A/0.525
3ddcGNPGTPase HRas/0.524
3rabGNPRas-related protein Rab-3A/0.522
3v4fGNPGTPase HRas/0.522
4cymGCPRas-related protein Rab-32/0.522
4dltGNPGTPase HRas/0.522
4qxaGTPRas-related protein Rab-9A/0.521
1zc4GNPRas-related protein Ral-A/0.520
3ea5GDPGTP-binding nuclear protein Ran/0.520
3a58GNPGTP-binding protein RHO1/0.519
4nyjGNPGTPase HRas/0.519
5jljGNPGTP-binding nuclear protein Ran/0.518
1g17GNPRas-related protein SEC4/0.514
3lbnGNPGTPase HRas/0.514
3oivGNPGTPase HRas/0.514
5hpyGDPTransforming protein RhoA/0.512
1zd9GDPADP-ribosylation factor-like protein 8A/0.510
1e96GTPRas-related C3 botulinum toxin substrate 1/0.509
1ibrGNPGTP-binding nuclear protein Ran/0.508
4mitGTPRho-related protein racC/0.508
4rkfGNPRas-related protein Rab-3/0.506
1zc3GNPRas-related protein Ral-A/0.503
2bkuGTPGTP-binding nuclear protein Ran/0.503
4k81GTPGTPase HRas/0.503
1k5dGNPGTP-binding nuclear protein Ran/0.501
3kucGDPRas-related protein Rap-1A/0.500
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.497
3bc1GNPRas-related protein Rab-27A/0.496
3i3sGNPGTPase HRas/0.496
3tsoGNPRas-related protein Rab-25/0.496
4nyiGNPGTPase HRas/0.493
1lfdGNPGTPase HRas/0.490
4js0GNPCell division control protein 42 homolog/0.490
1kmqGNPTransforming protein RhoA/0.489
3kkoGNPRas-related protein M-Ras/0.488
3rs5GNPGTPase HRas/0.488
3kz1GSPTransforming protein RhoA/0.487
3tnfGNPRas-related protein Rab-8A/0.487
4ol0GTPGTP-binding nuclear protein Ran/0.486
4kvgGTPRas-related protein Rap-1A/0.485
5b2zGNPGTPase HRas/0.485
3eg5GNPCell division control protein 42 homolog/0.484
3l8yGNPGTPase HRas/0.484
4g0nGNPGTPase HRas/0.481
3pitGNPRas-related protein M-Ras/0.480
3tklGTPRas-related protein Rab-1A/0.480
2c5lGTPGTPase HRas/0.479
3lbhGNPGTPase HRas/0.478
1a2bGSPTransforming protein RhoA/0.476
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.476
2rgeGNPGTPase HRas/0.476
2rgbGNPGTPase HRas/0.475
3wyfGTPGTP-binding nuclear protein/0.473
3x1zGNPRas-related protein Rap-1b/0.470
1ow3GDPTransforming protein RhoA/0.466
3qbtGNPRas-related protein Rab-8A/0.464
4uj3GNPRas-related protein Rab-11A/0.464
1m7bGTPRho-related GTP-binding protein RhoE/0.463
3mjhGTPRas-related protein Rab-5A/0.462
4lucGDPGTPase KRas/0.462
4xoiGTPTransforming protein RhoA/0.462
2ql6ADPNicotinamide riboside kinase 1/0.461
2rgcGNPGTPase HRas/0.460
5difGNPGTP-binding nuclear protein Ran/0.460
2fg5GNPRas-related protein Rab-31/0.459
1s1cGNPTransforming protein RhoA/0.458
3cphGDPRas-related protein SEC4/0.458
4uj5GNPRas-related protein Rab-11A/0.458
1oixGDPRas-related protein Rab-11A/0.457
3oiwGNPGTPase HRas/0.457
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.456
1cxzGSPTransforming protein RhoA/0.455
2gcpGSPRho-related GTP-binding protein RhoC/0.455
4dsnGCPGTPase KRas/0.455
3kudGDPGTPase HRas/0.454
4o2rGDPGTP-binding protein Rheb/0.454
2gvdGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.453
3rs7GNPGTPase HRas/0.453
2w2xGSPRas-related C3 botulinum toxin substrate 2/0.452
4epxGDPGTPase KRas/0.452
2clsGTPRho-related GTP-binding protein Rho6/0.451
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.451
4dlsGNPGTPase HRas/0.451
4hdoGNPRas-related protein Rap-1b/0.448
4tyqAP5Adenylate kinase/0.448
3lbiGNPGTPase HRas/0.447
4xvrGNPGTPase HRas/0.446
1uadGNPRas-related protein Ral-A/0.444
4dlwGNPGTPase HRas/0.442
4ohxADPProtein clpf-1/0.441
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.440