sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 1.000 | |
| 1z2p | ACP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.824 | |
| 2vqd | AP2 | Biotin carboxylase | 6.3.4.14 | 0.502 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.489 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.474 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.463 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4o4i | ACP | Tubulin tyrosine ligase | / | 0.462 | |
| 3wo1 | ADP | Alanine--anticapsin ligase | / | 0.461 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.458 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.452 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.451 | |
| 3rv4 | ADP | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 5la6 | ACP | Tubulin tyrosine ligase | / | 0.448 | |
| 2ou5 | FMN | Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein | / | 0.446 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.444 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.441 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.441 | |
| 1dj2 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.440 | |
| 4die | C5P | Cytidylate kinase | / | 0.440 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.440 |