sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1yhn | GTP | Ras-related protein Rab-7a |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1yhn | GTP | Ras-related protein Rab-7a | / | 1.000 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.611 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.604 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.596 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.593 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.586 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.577 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.570 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.561 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.561 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.550 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.549 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.547 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.547 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.546 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.535 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.532 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.531 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.529 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.525 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.522 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.514 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.511 | |
| 3lbn | GNP | GTPase HRas | / | 0.509 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.508 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.500 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.497 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.496 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.496 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.493 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.491 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.489 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.488 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.486 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.484 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.484 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.482 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.482 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.479 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.479 | |
| 3i3s | GNP | GTPase HRas | / | 0.479 | |
| 3rs5 | GNP | GTPase HRas | / | 0.479 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.478 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.477 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.476 | |
| 4dlw | GNP | GTPase HRas | / | 0.476 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.473 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.473 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.472 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.472 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.468 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.468 | |
| 4dlt | GNP | GTPase HRas | / | 0.468 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.466 | |
| 2c5l | GTP | GTPase HRas | / | 0.464 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.462 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.461 | |
| 4k81 | GTP | GTPase HRas | / | 0.461 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.461 | |
| 4nyj | GNP | GTPase HRas | / | 0.457 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.454 | |
| 3v4f | GNP | GTPase HRas | / | 0.454 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.453 | |
| 3ddc | GNP | GTPase HRas | / | 0.453 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.451 | |
| 4mit | GTP | Rho-related protein racC | / | 0.450 | |
| 2rge | GNP | GTPase HRas | / | 0.449 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.449 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.448 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.447 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.447 | |
| 3oiu | GNP | GTPase HRas | / | 0.446 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.445 | |
| 3oiv | GNP | GTPase HRas | / | 0.445 | |
| 4nyi | GNP | GTPase HRas | / | 0.444 | |
| 3kud | GDP | GTPase HRas | / | 0.443 | |
| 3l8y | GNP | GTPase HRas | / | 0.443 | |
| 2rgb | GNP | GTPase HRas | / | 0.442 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.442 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.441 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.440 |