scPDB - Distribution of Binding site Similarity values of 1xag entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1xag	NAD	3-dehydroquinate synthase

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1xag	NAD	3-dehydroquinate synthase	/	1.000
1xah	NAD	3-dehydroquinate synthase	/	0.522
1q0r	AKT	Aclacinomycin methylesterase RdmC	3.1.1.95	0.465
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.458
1q0z	AKA	Aclacinomycin methylesterase RdmC	3.1.1.95	0.451
2g24	7IG	Renin	3.4.23.15	0.448
4bft	ZVT	Pantothenate kinase	2.7.1.33	0.441