sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1x88 | NAT | Kinesin-like protein KIF11 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1x88 | NAT | Kinesin-like protein KIF11 | / | 1.000 | |
| 2x7c | KZ9 | Kinesin-like protein KIF11 | / | 0.656 | |
| 3k5e | K5E | Kinesin-like protein KIF11 | / | 0.651 | |
| 2x7e | X7E | Kinesin-like protein KIF11 | / | 0.620 | |
| 2x7d | EGB | Kinesin-like protein KIF11 | / | 0.609 | |
| 2ieh | MOY | Kinesin-like protein KIF11 | / | 0.603 | |
| 1q0b | NAT | Kinesin-like protein KIF11 | / | 0.600 | |
| 2q2z | MKK | Kinesin-like protein KIF11 | / | 0.595 | |
| 3k3b | L31 | Kinesin-like protein KIF11 | / | 0.591 | |
| 2fme | 3QC | Kinesin-like protein KIF11 | / | 0.585 | |
| 2g1q | N9H | Kinesin-like protein KIF11 | / | 0.581 | |
| 4bbg | V02 | Kinesin-like protein KIF11 | / | 0.579 | |
| 2x2r | X2O | Kinesin-like protein KIF11 | / | 0.576 | |
| 2xae | 2XA | Kinesin-like protein KIF11 | / | 0.570 | |
| 3ken | ZZD | Kinesin-like protein KIF11 | / | 0.563 | |
| 2wog | ZZD | Kinesin-like protein KIF11 | / | 0.555 | |
| 4a51 | DQ8 | Kinesin-like protein KIF11 | / | 0.554 | |
| 2gm1 | 2AZ | Kinesin-like protein KIF11 | / | 0.544 | |
| 4a5y | G7X | Kinesin-like protein KIF11 | / | 0.485 | |
| 4as7 | 6LX | Kinesin-like protein KIF11 | / | 0.465 | |
| 1eio | GCH | Gastrotropin | / | 0.460 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.459 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.451 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.446 | |
| 2cdu | FAD | NADH oxidase | / | 0.445 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.443 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.441 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3gi3 | B10 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.440 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.440 |