Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1wuq | 8GT | GTP cyclohydrolase 1 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
1wuq | 8GT | GTP cyclohydrolase 1 | / | 1.000 | |
1wur | 8DG | GTP cyclohydrolase 1 | / | 0.584 | |
4du6 | GTP | GTP cyclohydrolase 1 | / | 0.464 | |
1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.459 | |
2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.459 | |
1r2j | FAD | FkbI | / | 0.457 | |
3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.455 | |
3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.448 | |
1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.446 | |
3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.445 | |
2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.444 | |
3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.444 | |
2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.443 |