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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ve3SAMUncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1ve3SAMUncharacterized protein/1.000
3ha5SFGHydroxymycolate synthase MmaA42.1.10.478
4iv0SAMPhosphoethanolamine N-methyltransferase, putative/0.478
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.475
5irnADPNucleotide binding oligomerization domain containing 2/0.470
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.468
1c7oPPGHemolysin/0.465
1nbiSAMGlycine N-methyltransferase2.1.1.200.465
2iko7IGRenin3.4.23.150.452
2eg5SAH7-methylxanthosine synthase 1/0.451
1r2jFADFkbI/0.450
2xvfFADPutative flavin-containing monooxygenase/0.450
2g1s4IGRenin3.4.23.150.449
5bp9SAHPutative methyltransferase protein/0.449
1qzzSAMAclacinomycin 10-hydroxylase RdmB4.1.10.446
2g226IGRenin3.4.23.150.445
2gs9SAHUncharacterized protein/0.444
3gw9VNILanosterol 14-alpha-demethylase/0.443
2fk8SAMHydroxymycolate synthase MmaA42.1.10.441
3sn6P0GBeta-2 adrenergic receptor/0.441
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.440
1rneC60Renin3.4.23.150.440