sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uxj | NAD | Malate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1uxj | NAD | Malate dehydrogenase | / | 1.000 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.578 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.548 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.525 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.524 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.523 | |
| 1gv0 | NAD | Malate dehydrogenase | / | 0.517 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.515 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.514 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.514 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.510 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.509 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.502 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.502 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.492 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.488 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.486 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.482 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.482 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.481 | |
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.480 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.470 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.464 | |
| 4ros | APR | Malate dehydrogenase | / | 0.462 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.461 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.455 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.453 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.453 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.449 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.448 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.445 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.445 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.444 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.443 | |
| 4uun | NAI | L-lactate dehydrogenase | / | 0.442 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.441 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.440 |