sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 1.000 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.571 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.557 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.554 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.544 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.536 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.516 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.511 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.505 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.502 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.499 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.499 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.494 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.486 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.484 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.480 | |
| 4irn | FAD | AnaB | / | 0.475 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.473 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.470 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.470 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.470 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.449 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.443 |