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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1tu3GNPRas-related protein Rab-5A

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1tu3GNPRas-related protein Rab-5A/1.000
3mjhGTPRas-related protein Rab-5A/0.512
4uj5GNPRas-related protein Rab-11A/0.466
4uj3GNPRas-related protein Rab-11A/0.462
2ic5GDPRas-related C3 botulinum toxin substrate 3/0.454
1n6lGTPRas-related protein Rab-5A/0.453
3wygGTPGTP-binding nuclear protein GSP1/CNR1/0.452
4ol0GTPGTP-binding nuclear protein Ran/0.450
4hdqGNPRas-related protein Rap-1b/0.442
3w3zGTPGTP-binding nuclear protein Ran/0.441
4d0lGSPRas-related protein Rab-11A/0.441
3t1tGDPProbable gliding protein mglA/0.440