Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1tdfFADThioredoxin reductase1.8.1.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1tdfFADThioredoxin reductase1.8.1.91.000
1tdeFADThioredoxin reductase1.8.1.90.696
1trbFADThioredoxin reductase1.8.1.90.660
1cl0FADThioredoxin reductase1.8.1.90.622
4jnqFDAThioredoxin reductase/0.504
3ctyFADProbable thioredoxin reductase/0.467
2q0kFADThioredoxin reductase1.8.1.90.465
4ccrFADThioredoxin reductase/0.461
1fl2FADAlkyl hydroperoxide reductase subunit F1.8.10.459
4cbqFADThioredoxin reductase/0.454
1k4qFADGlutathione reductase, mitochondrial1.8.1.70.453
3itjFADThioredoxin reductase 11.8.1.90.452
4a5lFADThioredoxin reductase/0.448
4ccqFADThioredoxin reductase/0.448
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.446
4up3FADThioredoxin reductase/0.443
3ishFADThioredoxin reductase1.8.1.90.441