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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.637
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.632
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.630
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.621
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.584
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.573
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.571
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.571
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.564
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.537
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.518
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.505
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440