scPDB - Distribution of Binding site Similarity values of 1rd7 entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1rd7	FOL	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	1.000
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.586
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.568
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.567
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.554
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.553
5hi6	MTX	Dihydrofolate reductase	/	0.550
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.549
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.548
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.547
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.547
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.545
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.542
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.536
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.534
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.530
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.525
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.522
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.520
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.519
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.517
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.516
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.505
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.503
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.503
1ra3	MTX	Dihydrofolate reductase	1.5.1.3	0.497
4x5f	FOL	Dihydrofolate reductase	1.5.1.3	0.496
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.493
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.488
4i13	FOL	Dihydrofolate reductase	1.5.1.3	0.477
4x5h	FOL	Dihydrofolate reductase	1.5.1.3	0.463
4x5g	FOL	Dihydrofolate reductase	1.5.1.3	0.460
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.458
4qi9	MTX	Dihydrofolate reductase	/	0.458
5cc9	DDF	Dihydrofolate reductase	1.5.1.3	0.450
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.447
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.445
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.444
1ia4	TQ6	Dihydrofolate reductase	1.5.1.3	0.440