scPDB - Distribution of Binding site Similarity values of 1rc4 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1rc4	DDF	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	1.000
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.580
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.570
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.540
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.535
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.528
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.526
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.523
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.521
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.519
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.516
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.515
5hi6	MTX	Dihydrofolate reductase	/	0.514
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.504
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.503
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.501
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.497
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.492
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.491
4i13	FOL	Dihydrofolate reductase	1.5.1.3	0.491
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.490
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.486
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.486
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.485
4qi9	MTX	Dihydrofolate reductase	/	0.478
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.475
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.472
5cc9	DDF	Dihydrofolate reductase	1.5.1.3	0.470
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.470
1rx4	DDF	Dihydrofolate reductase	1.5.1.3	0.467
1rx6	DDF	Dihydrofolate reductase	1.5.1.3	0.464
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.464
4ele	31I	Dihydrofolate reductase	/	0.464
1rx5	DDF	Dihydrofolate reductase	1.5.1.3	0.460
1bzf	TMQ	Dihydrofolate reductase	1.5.1.3	0.459
2qk8	MTX	Dihydrofolate reductase	/	0.459
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.457
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.452
1rg7	MTX	Dihydrofolate reductase	1.5.1.3	0.452
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.447
4elb	34S	Dihydrofolate reductase	/	0.445
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.442
1dis	BDM	Dihydrofolate reductase	1.5.1.3	0.440