scPDB - Distribution of Binding site Similarity values of 1rb2 entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1rb2	FOL	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	1.000
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.620
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.615
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.610
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.607
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.606
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.605
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.603
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.600
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.590
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.589
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.581
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.580
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.571
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.566
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.566
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.564
5hi6	MTX	Dihydrofolate reductase	/	0.558
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.554
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.554
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.553
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.548
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.523
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.514
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.511
1ra3	MTX	Dihydrofolate reductase	1.5.1.3	0.501
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.499
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.482
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.482
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.476
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.474
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.472
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.470
1rx5	DDF	Dihydrofolate reductase	1.5.1.3	0.469
1jio	DEB	6-deoxyerythronolide B hydroxylase	/	0.463
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.461
5hs1	VOR	Lanosterol 14-alpha demethylase	/	0.461
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.460
4yao	FMN	NADPH--cytochrome P450 reductase	/	0.454
3s7a	684	Dihydrofolate reductase	1.5.1.3	0.453
4x5h	FOL	Dihydrofolate reductase	1.5.1.3	0.453
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.452
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.451
1ia4	TQ6	Dihydrofolate reductase	1.5.1.3	0.449
4i13	FOL	Dihydrofolate reductase	1.5.1.3	0.448
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.447
1rx6	DDF	Dihydrofolate reductase	1.5.1.3	0.443
1ia3	TQ5	Dihydrofolate reductase	1.5.1.3	0.442
2cig	1DG	Dihydrofolate reductase	1.5.1.3	0.441
4ele	31I	Dihydrofolate reductase	/	0.441