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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1qsnCOAHAT A1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1qsnCOAHAT A1/1.000
1puaCOAHAT A1/0.584
1pu9COAHAT A1/0.522
1cm0COAHistone acetyltransferase KAT2B2.3.1.480.480
2g1n1IGRenin3.4.23.150.461
1qsrACOHAT A1/0.459
3zoiM2WIsopenicillin N synthase1.21.3.10.458
1yhjR6CPyridoxal kinase2.7.1.350.454
3tfyCOAN-alpha-acetyltransferase 502.3.10.450
2po7CHDFerrochelatase, mitochondrial4.99.1.10.448
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.444
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
3fktSIIBeta-secretase 13.4.23.460.442
5dp2NAPCurF/0.442
5kf2ACOPredicted acetyltransferase/0.441
1oc1ASVIsopenicillin N synthase1.21.3.10.440
3oadLPORenin3.4.23.150.440
4e2yJHZMethyltransferase/0.440
5kf8ACOPredicted acetyltransferase/0.440