Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1pp9SMACytochrome b

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1pp9SMACytochrome b/1.000
1ppjSMACytochrome b/0.671
3h1jSMACytochrome b/0.553
3cx5SMACytochrome b/0.547
2qjySMACytochrome b/0.540
1kyoSMACytochrome b/0.537
1kb9SMACytochrome b/0.526
3cxhSMACytochrome b/0.524
2yiuSMACytochrome b/0.523
1ezvSMACytochrome b/0.521
2ibzSMACytochrome b/0.519
2qjpSMACytochrome b/0.514
3p99LNPLanosterol 14-alpha-demethylase/0.471
3gc8B45Mitogen-activated protein kinase 112.7.11.240.456
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.455
3vspEK8Peroxisome proliferator-activated receptor gamma/0.453
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.453
2ath3EAPeroxisome proliferator-activated receptor gamma/0.452
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.452
3abaFLICytochrome P450/0.451
4g7gVFVLanosterol 14-alpha-demethylase/0.451
1fm9570Peroxisome proliferator-activated receptor gamma/0.449
3dxjNE6DNA-directed RNA polymerase subunit beta/0.449
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.449
2y00Y01Beta-1 adrenergic receptor/0.448
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.448
2y01Y01Beta-1 adrenergic receptor/0.447
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4q72FADBifunctional protein PutA/0.442
2nnhREACytochrome P450 2C8/0.440