sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 1.000 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.623 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.559 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.529 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.526 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.509 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.506 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.500 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.495 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.491 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.488 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.485 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.479 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.468 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.467 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.465 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.464 | |
| 2zw5 | COA | Bleomycin acetyltransferase | / | 0.464 | |
| 3r96 | ACO | MccE protein | / | 0.459 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.458 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.451 | |
| 4p63 | NAD | Probable deoxyhypusine synthase | 2.5.1.46 | 0.450 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.449 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.448 | |
| 5dp2 | NAP | CurF | / | 0.446 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.444 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.444 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.443 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.442 |