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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ovmTPPIndole-3-pyruvate decarboxylase4.1.1.74

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1ovmTPPIndole-3-pyruvate decarboxylase4.1.1.741.000
2vk8TPPPyruvate decarboxylase isozyme 1/0.532
2w93TPPPyruvate decarboxylase isozyme 1/0.526
2vk4TPPPyruvate decarboxylase4.1.1.10.524
1pvdTPPPyruvate decarboxylase isozyme 1/0.517
4zp1TPPPyruvate decarboxylase4.1.1.10.483
1qpbTPPPyruvate decarboxylase isozyme 1/0.475
2q5qTPWIndole-3-pyruvate decarboxylase4.1.1.740.475
3qxpX64Cyclin-dependent kinase 22.7.11.220.452
4cokTPPPyruvate decarboxylase/0.452
3oe1TDLPyruvate decarboxylase4.1.1.10.449
3rak03ZCyclin-dependent kinase 22.7.11.220.449
2q5oTPWIndole-3-pyruvate decarboxylase4.1.1.740.448