scPDB - Distribution of Binding site Similarity values of 1ohk entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1ohk	COP	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1ohk	COP	Dihydrofolate reductase	1.5.1.3	1.000
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.570
1u72	MTX	Dihydrofolate reductase	1.5.1.3	0.561
2w3m	FOL	Dihydrofolate reductase	1.5.1.3	0.561
4keb	FOL	Dihydrofolate reductase	1.5.1.3	0.555
4m6k	FOL	Dihydrofolate reductase	1.5.1.3	0.542
3ghw	GHW	Dihydrofolate reductase	1.5.1.3	0.536
3l3r	OAG	Dihydrofolate reductase	1.5.1.3	0.529
4eil	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.525
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.524
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.521
3gi2	GHW	Dihydrofolate reductase	1.5.1.3	0.519
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.517
1kms	LIH	Dihydrofolate reductase	1.5.1.3	0.517
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.517
1ohj	COP	Dihydrofolate reductase	1.5.1.3	0.513
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.512
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.505
3ntz	3TZ	Dihydrofolate reductase	1.5.1.3	0.489
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.488
4kfj	FOL	Dihydrofolate reductase	1.5.1.3	0.488
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.487
1dls	MTX	Dihydrofolate reductase	1.5.1.3	0.487
3d80	Q22	Dihydrofolate reductase	1.5.1.3	0.485
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.481
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.481
1hfp	MOT	Dihydrofolate reductase	1.5.1.3	0.480
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.479
3gyf	51P	Dihydrofolate reductase	1.5.1.3	0.467
3nu0	3TU	Dihydrofolate reductase	1.5.1.3	0.465
1pd8	CO4	Dihydrofolate reductase	1.5.1.3	0.462
3ghv	GHC	Dihydrofolate reductase	1.5.1.3	0.459
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.452
3k45	51P	Dihydrofolate reductase	1.5.1.3	0.450
3qly	55V	Uncharacterized protein	/	0.448
1u70	MTX	Dihydrofolate reductase	1.5.1.3	0.447
1kmv	LII	Dihydrofolate reductase	1.5.1.3	0.442