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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1npdNADQuinate/shikimate dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1npdNADQuinate/shikimate dehydrogenase/1.000
3t4eNADQuinate/shikimate dehydrogenase/0.604
1vi2NADQuinate/shikimate dehydrogenase/0.597
1o9bNAIQuinate/shikimate dehydrogenase/0.596
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.512
2cy0NAPShikimate dehydrogenase (NADP(+))/0.506
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.496
3tnlNADShikimate dehydrogenase (NADP(+))/0.495
1nvtNAPShikimate dehydrogenase (NADP(+))/0.487
2hk9NAPShikimate dehydrogenase (NADP(+))/0.482
2ev9NAPShikimate dehydrogenase (NADP(+))/0.478
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.468
4k28NADShikimate dehydrogenase family protein/0.459
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.454
1amoNAPNADPH--cytochrome P450 reductase/0.452
1nzdUPGDNA beta-glucosyltransferase/0.449
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.449
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.449
3apwDP0Alpha-1-acid glycoprotein 2/0.443