Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1nhz486Glucocorticoid receptor

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1nhz486Glucocorticoid receptor/1.000
2ovhAS0Progesterone receptor/0.557
2ovmAS0Progesterone receptor/0.524
2w8y486Progesterone receptor/0.493
4r21STRCytochrome P450 family 17 polypeptide 2/0.484
1m9m6NINitric oxide synthase, endothelial1.14.13.390.465
4r20AERCytochrome P450 family 17 polypeptide 2/0.465
4a2jAS0Progesterone receptor/0.462
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.452
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.450
4enhFVXCholesterol 24-hydroxylase/0.450
1s9pDESEstrogen-related receptor gamma/0.449
3mdmFJZCholesterol 24-hydroxylase/0.449
3tk3CPZCytochrome P450 2B41.14.14.10.449
1p93DEXGlucocorticoid receptor/0.447
1pkfEPDEpothilone C/D epoxidase1.140.445
1s9qOHTEstrogen-related receptor gamma/0.445
3d90NOGProgesterone receptor/0.445
3p99LNPLanosterol 14-alpha-demethylase/0.441
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4v2gITCTetracycline repressor protein class D/0.440