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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.59

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.591.000
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.587
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.520
4q71FADBifunctional protein PutA/0.463
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.456
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.450
4esoNAPPutative oxidoreductase/0.450
1tj0FADBifunctional protein PutA1.5.5.20.443
1lf3EH5Plasmepsin-23.4.23.390.441
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.441
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.441
4q72FADBifunctional protein PutA/0.441
2he5NDPAldo-keto reductase family 1 member C211.1.10.440