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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1mj9COAHistone acetyltransferase ESA1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1mj9COAHistone acetyltransferase ESA1/1.000
1fy7COAHistone acetyltransferase ESA1/0.754
1mjaCOAHistone acetyltransferase ESA1/0.743
1mjbACOHistone acetyltransferase ESA1/0.709
3to6LYS_CMCHistone acetyltransferase ESA1/0.654
2ou2ACOHistone acetyltransferase KAT5/0.627
2y0mACOHistone acetyltransferase KAT8/0.598
2givACOHistone acetyltransferase KAT8/0.560
2ozuACOHistone acetyltransferase KAT6A/0.493
1p0hCOAMycothiol acetyltransferase2.3.1.1890.467
2rc4ACOHistone acetyltransferase KAT6A/0.467
3b70NAPEnoyl reductase LovC10.448
1ozpACOMycothiol acetyltransferase2.3.1.1890.447