scPDB - Distribution of Binding site Similarity values of 1kyx entry / Site 4

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	1.000
2a57	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.624
2a59	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.620
1kyv	RBF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.581
1kyy	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.578
1ejb	INJ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.555
2a58	RBF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.543
4kq6	DLZ	6,7-dimethyl-8-ribityllumazine synthase	/	0.511
1nqu	RDL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.507
1w29	TS0	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.505
1nqv	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.489
1w19	T5P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.478
1nqw	5YL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.468
2vi5	Y19	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.463
1rvv	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.459
1w19	T4P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.453
2o6h	INI	6,7-dimethyl-8-ribityllumazine synthase 1	2.5.1.78	0.449