Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1i44 | ACP | Insulin receptor | 2.7.10.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1i44 | ACP | Insulin receptor | 2.7.10.1 | 1.000 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.478 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.461 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.459 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.451 | |
| 1jqh | ANP | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.449 | |
| 4c3p | ACP | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.446 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 4xlv | ACP | Insulin receptor | 2.7.10.1 | 0.442 |