sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1fy7 | COA | Histone acetyltransferase ESA1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 1.000 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.911 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.891 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.750 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.647 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.623 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.579 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.545 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.485 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.466 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.461 |