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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.62

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.621.000
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.570
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.534
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.513
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.492
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.492
1cf3FADGlucose oxidase1.1.3.40.459
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.445
5dbfNDPIridoid synthase1.3.1.990.445
3q43D66M1 family aminopeptidase3.4.110.443
5dbgNADIridoid synthase1.3.1.990.441
5emhNAPIridoid synthase1.3.1.990.441
2vbdV10Isopenicillin N synthase1.21.3.10.440