scPDB - Distribution of Binding site Similarity values of 1dhj entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1dhj	MTX	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	1.000
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.787
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.677
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.659
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.641
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.614
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.607
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.602
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.591
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.589
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.560
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.542
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.540
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.519
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.517
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.516
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.508
5hi6	MTX	Dihydrofolate reductase	/	0.504
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.503
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.476
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.462
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.460
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.451
3a1n	NAD	NDP-sugar epimerase	/	0.444
4ele	31I	Dihydrofolate reductase	/	0.440