scPDB - Distribution of Binding site Similarity values of 1dds entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1dds	MTX	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1dds	MTX	Dihydrofolate reductase	1.5.1.3	1.000
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.695
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.614
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.607
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.598
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.589
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.583
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.578
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.562
5hi6	MTX	Dihydrofolate reductase	/	0.552
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.550
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.543
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.543
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.535
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.520
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.517
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.509
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.508
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.506
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.498
1ra3	MTX	Dihydrofolate reductase	1.5.1.3	0.495
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.485
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.483
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.472
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.472
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.471
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.467
4ele	31I	Dihydrofolate reductase	/	0.466
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.461
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.459
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.455
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.454
3fl8	RAR	Dihydrofolate reductase	/	0.450
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.450
4elb	34R	Dihydrofolate reductase	/	0.445
4x5f	FOL	Dihydrofolate reductase	1.5.1.3	0.444
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.440
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.440