scPDB - Distribution of Binding site Similarity values of 1ddr entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1ddr	MTX	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	1.000
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.712
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.646
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.634
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.622
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.618
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.612
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.611
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.597
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.591
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.585
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.579
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.567
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.551
5hi6	MTX	Dihydrofolate reductase	/	0.548
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.533
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.529
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.516
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.515
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.503
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.494
1ra3	MTX	Dihydrofolate reductase	1.5.1.3	0.491
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.480
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.470
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.469
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.467
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.467
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.462
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.455
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.453
4ele	31I	Dihydrofolate reductase	/	0.452
4elb	34S	Dihydrofolate reductase	/	0.448
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.445
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.443
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.443