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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1bxkNADdTDP-glucose 4,6-dehydratase 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1bxkNADdTDP-glucose 4,6-dehydratase 2/1.000
1g1aNADdTDP-glucose 4,6-dehydratase/0.601
4egbNADdTDP-glucose 4,6-dehydratase/0.520
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.505
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.468
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.467
3ru7NADUDP-N-acetylglucosamine 4-epimerase/0.456
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.456
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.455
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.450
2p5uNADUDP-glucose 4-epimerase/0.448
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.447
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.444
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.444