scPDB - Distribution of Binding site Similarity values of 1arg entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1arg	PPD	Aspartate aminotransferase	2.6.1.1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1arg	PPD	Aspartate aminotransferase	2.6.1.1	1.000
1x28	PGU	Aspartate aminotransferase	2.6.1.1	0.612
1ahg	TYR_PLP	Aspartate aminotransferase	2.6.1.1	0.594
1arh	PPD	Aspartate aminotransferase	2.6.1.1	0.592
3qpg	3QP	Aspartate aminotransferase	2.6.1.1	0.562
1cq8	PY6	Aspartate aminotransferase	2.6.1.1	0.561
1cq6	PY4	Aspartate aminotransferase	2.6.1.1	0.554
1asc	NPL	Aspartate aminotransferase	2.6.1.1	0.543
1akc	PPE	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.541
4rkd	KET	Aminotransferase	/	0.533
1oxo	IK2	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.529
1akb	PPD	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.528
4dbc	3QP	Aspartate aminotransferase	2.6.1.1	0.528
1cq7	PY5	Aspartate aminotransferase	2.6.1.1	0.522
1maq	PGU	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.517
1toi	HCI	Aspartate aminotransferase	2.6.1.1	0.510
4ge9	0L0	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.508
1ivr	CBA	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.506
1map	KET	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.505
1aka	PLP	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.491
1tou	B1V	Fatty acid-binding protein, adipocyte	/	0.478
4w5k	PLP	Aspartate aminotransferase, mitochondrial	/	0.475
1u1g	BBB	Uridine phosphorylase	2.4.2.3	0.472
1toj	HCI	Aspartate aminotransferase	2.6.1.1	0.468
1tow	CRZ	Fatty acid-binding protein, adipocyte	/	0.468
1u1f	183	Uridine phosphorylase	2.4.2.3	0.467
2ea4	F79	Methionine aminopeptidase 2	/	0.464
3h3t	16H	Collagen type IV alpha-3-binding protein	/	0.464
3tfu	PL8	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	2.6.1.62	0.462
4je5	PLP	Aromatic/aminoadipate aminotransferase 1	2.6.1.39	0.462
4emy	PLP	Aminotransferase class I and II	/	0.461
4fl0	PLP	Aminotransferase ALD1, chloroplastic	2.6.1	0.461
3fr5	I4A	Fatty acid-binding protein, adipocyte	/	0.460
1rft	PXM	Pyridoxal kinase	2.7.1.35	0.458
1w19	T5P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.457
3ei8	PL5	LL-diaminopimelate aminotransferase, chloroplastic	/	0.457
1b9i	PXG	3-amino-5-hydroxybenzoate synthase	4.2.1.144	0.456
1yw8	A75	Methionine aminopeptidase 2	/	0.455
4wlj	IK2	Kynurenine--oxoglutarate transaminase 1	2.6.1.7	0.455
1yci	NDF	Hypoxia-inducible factor 1-alpha inhibitor	1.14.11.30	0.453
2ykv	IK2	Beta-transaminase	/	0.452
3fr4	F8A	Fatty acid-binding protein, adipocyte	/	0.449
4nhy	PD2	Prolyl 3-hydroxylase OGFOD1	1.14.11	0.449
3aej	AA5	Methionine gamma-lyase	/	0.447
2q0g	UPU	Poly(A) polymerase, putative	/	0.445
1gtr	ATP	Glutamine--tRNA ligase	6.1.1.18	0.444
1nm6	L86	Prothrombin	3.4.21.5	0.444
2fhj	H4Z	Formylmethanofuran--tetrahydromethanopterin formyltransferase	2.3.1.101	0.444
4jey	PLP	Acetylornithine/succinyldiaminopimelate aminotransferase	2.6.1.11	0.444
1kbo	340	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.443
1ygk	RRC	Pyridoxal kinase	2.7.1.35	0.443
2gev	COK	Pantothenate kinase	2.7.1.33	0.442
3h3q	H13	Collagen type IV alpha-3-binding protein	/	0.442
4aoa	IK2	Beta-phenylalanine transaminase	2.6.1	0.442
3iel	U5P	Ribonuclease TTHA0252	3.1	0.441
3q43	D66	M1 family aminopeptidase	3.4.11	0.441
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.441
3sqz	COA	Putative hydroxymethylglutaryl-CoA synthase	/	0.440