sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 1.000 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.679 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.615 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.596 | |
| 1map | KET | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.595 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.589 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.565 | |
| 1maq | PGU | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.561 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.560 | |
| 1cq6 | PY4 | Aspartate aminotransferase | 2.6.1.1 | 0.541 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.529 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.522 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.517 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.505 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.471 | |
| 4e2y | JHZ | Methyltransferase | / | 0.462 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.459 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.459 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.456 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.454 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.453 | |
| 1x28 | PGU | Aspartate aminotransferase | 2.6.1.1 | 0.453 | |
| 1arg | PPD | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.442 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.442 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 |