Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4qo9 627 Serine/threonine-protein kinase 24 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4qo9 627Serine/threonine-protein kinase 24 2.7.11.1 0.956
2bmc MPYAurora kinase A 2.7.11.1 0.675
2xba 571ALK tyrosine kinase receptor 2.7.10.1 0.669
2v7a 627Tyrosine-protein kinase ABL1 2.7.10.2 0.661
2c4g 514Cyclin-dependent kinase 2 2.7.11.22 0.655
2j4z 626Aurora kinase A 2.7.11.1 0.655