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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4lyn 1YG Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
4lyn 1YGCyclin-dependent kinase 2 2.7.11.22 0.948
4fkj 11KCyclin-dependent kinase 2 2.7.11.22 0.786
3igg EFQCyclin-dependent kinase 2 2.7.11.22 0.772
4fki 09KCyclin-dependent kinase 2 2.7.11.22 0.765
2a0c CK9Cyclin-dependent kinase 2 2.7.11.22 0.760
2btr U73Cyclin-dependent kinase 2 2.7.11.22 0.758
4e5i 0N9Polymerase acidic protein / 0.744
3dog NNNCyclin-dependent kinase 2 2.7.11.22 0.737
3pj8 404Cyclin-dependent kinase 2 2.7.11.22 0.733
2r64 740Cyclin-dependent kinase 2 2.7.11.22 0.718
1gih 1PUCyclin-dependent kinase 2 2.7.11.22 0.709
1vyz N5BCyclin-dependent kinase 2 2.7.11.22 0.706
3lfs A07Cyclin-dependent kinase 2 2.7.11.22 0.699
2a4l RRCCyclin-dependent kinase 2 2.7.11.22 0.698
1gii 1PUCyclin-dependent kinase 2 2.7.11.22 0.690
3ddq RRCCyclin-dependent kinase 2 2.7.11.22 0.686
4fkp LS5Cyclin-dependent kinase 2 2.7.11.22 0.682
3lfq A28Cyclin-dependent kinase 2 2.7.11.22 0.679
4fkw 62KCyclin-dependent kinase 2 2.7.11.22 0.674
2bts U32Cyclin-dependent kinase 2 2.7.11.22 0.673
4fkv 61KCyclin-dependent kinase 2 2.7.11.22 0.673
1vyw 292Cyclin-dependent kinase 2 2.7.11.22 0.672
3ggf GVDSerine/threonine-protein kinase 26 / 0.671
3qtq X35Cyclin-dependent kinase 2 2.7.11.22 0.671
4bgq 38RCyclin-dependent kinase-like 5 2.7.11.22 0.671
2r3m SCXCyclin-dependent kinase 2 2.7.11.22 0.670
1y91 CT9Cyclin-dependent kinase 2 2.7.11.22 0.666
3ezv EZVCyclin-dependent kinase 2 2.7.11.22 0.664
2b54 D05Cyclin-dependent kinase 2 2.7.11.22 0.663
4fkr 45KCyclin-dependent kinase 2 2.7.11.22 0.663
1ke6 LS2Cyclin-dependent kinase 2 2.7.11.22 0.662
3uli 1N3Cyclin-dependent kinase 2 2.7.11.22 0.661
3r8z Z63Cyclin-dependent kinase 2 2.7.11.22 0.660
4e5f 0N7Polymerase acidic protein / 0.660
1gij 2PUCyclin-dependent kinase 2 2.7.11.22 0.659
1ckp PVBCyclin-dependent kinase 2 2.7.11.22 0.658
2vtj LZ4Cyclin-dependent kinase 2 2.7.11.22 0.658
4fks 46KCyclin-dependent kinase 2 2.7.11.22 0.658
2r3r 6SCCyclin-dependent kinase 2 2.7.11.22 0.655
3r28 XA0Cyclin-dependent kinase 2 2.7.11.22 0.655
3qtz X42Cyclin-dependent kinase 2 2.7.11.22 0.651
3rkb 12ZCyclin-dependent kinase 2 2.7.11.22 0.650