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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4l8v NAP Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4l8v NAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.936
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.727
2ixb NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.713
3ec7 NADInositol 2-dehydrogenase / 0.712
3q2k NAIProbable oxidoreductase / 0.693
2ixa NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.684
3m2t NADProbable dehydrogenase / 0.677
3ntq NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.673
3oa2 NADUDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase / 0.668
3adp NAILambda-crystallin 1.1.1.45 0.660
3rbv NAPSugar 3-ketoreductase / 0.660
1evj NADGlucose--fructose oxidoreductase 1.1.99.28 0.656