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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4kio G5K Tyrosine-protein kinase ITK/TSK 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4kio G5KTyrosine-protein kinase ITK/TSK 2.7.10.2 0.992
4l7s G7KTyrosine-protein kinase ITK/TSK 2.7.10.2 0.837
4e5i 0N9Polymerase acidic protein / 0.744
4mf1 29YTyrosine-protein kinase ITK/TSK 2.7.10.2 0.674
4mf0 29ZTyrosine-protein kinase ITK/TSK 2.7.10.2 0.668